However, the occurrence rate of toxic liver lesion and multiple organ injures was lower in children group as compared with adults group. 肺损害、贫血、中毒性脑病的发生率儿童组比成人组高,而中毒性肝损害、多器官损害的发生率儿童组则比成人组低;
Conclusion It suggests that a three-month oral levodopa treatment should be not toxic for the remaining dopaminergic neurons in rats with a unilateral 6-OHDA lesion. 结论长期使用左旋多巴对6OHDA单侧损毁的PD大鼠残存的黑质DA能神经元无毒性作用。
Limb ischemia/ reperfusion injury is a complicated pathological process caused by many pathogenic factors, including oxygen free radicals, lipid peroxidation, intracellular calcium overload, toxic effect of excitatory neurotransmitters, inflammatory lesion and so on. 肢体再灌注损伤是一个复杂的病理过程,其致病因素包括氧自由基、脂质过氧化、细胞内Ca2+超载、兴奋性神经递质毒效应及炎性损害等多种病理机制。